Diffuse intrinsic pontine glioma (DIPG) is a type of brain tumor found in the pons, which is part of the brainstem. DIPG primarily affects children, with most diagnoses occurring between 5 and 7 years of age. DIPG makes up 10-15% of all brain tumors in children, with about 100-300 new diagnoses per year in the United States and a similar number in Europe. Unlike many other pediatric cancers, there has been little progress in improving treatments and cure rates for DIPG over the last few decades. Unfortunately, fewer than 10% of children with DIPG survive two years from diagnosis.
The name diffuse intrinsic pontine glioma describes how the tumor grows, where it is found, and what kinds of cells give rise to the tumor.